Why Choose Prescription Skincare

Hello Alpha Team

February 12, 2025

Whether you're dealing with stubborn acne in your 30s (yes, adult acne is incredibly common), noticing the signs of aging or dark spots, or struggling with sensitive skin—prescription formulas can target multiple concerns at the same time. 

Some of the most common issues we address include:

  • Acne: From occasional breakouts to persistent adult acne
  • Anti-aging: Fine lines, wrinkles, and loss of firmness
  • Hyperpigmentation: Dark spots and uneven skin tone
  • Rosacea: Redness, bumps, and irritation that require gentler approaches
  • Combination concerns: Because real skin rarely has just one issue

Understanding Your Prescription Ingredients

What makes Hello Alpha's formulations special is how we combine powerful active ingredients that work together. Depending on your skin assessment, your provider might include:

  • Tretinoin: The gold standard for both anti-aging and acne treatment, this prescription-only retinoid accelerates cell turnover, builds collagen, and creates transformative results over time. Tretinoin is up to 20 times more powerful than retinol, improving skin texture, fine lines, and wrinkles with consistent use.4

  • Niacinamide: This multitasking ingredient strengthens your skin barrier while tackling everything from oil regulation to redness reduction. Niacinamide plays well with other ingredients while calming inflammation and evening out skin tone—making it perfect for sensitive skin types that need extra care.5

  • Ivermectin & Metronidazole: Targets inflammatory rosacea by combating skin mites and providing anti-inflammatory benefits to reduce redness, bumps, and irritation—great for sensitive, reactive skin. Ivermectin works wonders for rosacea sufferers, helping to clear those stubborn bumps and redness that other treatments just can't tackle.6

  • Azelaic Acid: Especially beneficial for those struggling with both acne and pigmentation issues, this gentle yet effective acid brings clarity to your complexion. It fights both acne and the dark spots that often follow, all without causing irritation.8

  • Hyaluronic Acid*: Provides essential hydration that keeps your skin balanced while adjusting to active treatments. Did you know that this molecule can hold up to 1,000 times its weight in water? Hyaluronic acid gives your skin the hydration it deserves, helping to reduce the appearance of fine lines.9

  • Aloe*: Delivers immediate calming relief with healing compounds that reduce redness, draw moisture into the skin, and help it adapt to prescription-strength ingredients. Aloe soothes irritation and helps your skin absorb the other active ingredients.9

*These are inactive ingredients.

Your Skin Journey: Setting Realistic Expectations

We always emphasize the importance of patience with prescription skincare. Your journey will likely follow these stages:

  • Weeks 1-4: Become Acquainted
    Your skin is meeting powerful ingredients for the first time—and like any new relationship, there's an adjustment period. You might notice some dryness, slight redness, or even a few extra breakouts. Don't worry. This is your skin actively responding to the accelerated renewal process.
  • Months 1-3: See First Results
    This is when many patients start noticing improvements in texture and clarity. Your morning routine might become a moment of excitement as you observe subtle but meaningful changes. Studies show that approximately 68% of patients using prescription-strength formulations report noticeable improvements in skin texture and clarity by this time.10
  • Months 3-6: Enjoy the Compliments
    By now, others will likely notice your skin's improvement too. Those stubborn dark spots continue fading, breakouts become less frequent, and that healthy glow becomes more consistent.
  • Months 6+: Embrace Your Best Skin
    With continued use, your prescription formula becomes an essential part of maintaining your skin's health and preventing future concerns. Consistent use of prescription retinoids reduced the development of new fine lines by up to 87%.10 So keep at it!

How Hello Alpha Makes It Simple

With Hello Alpha, dermatology-grade care is formulated specifically for you. 

  1. Sign up for a Hello Alpha account
  2. Complete an online visit where a provider assesses your unique skin concerns
  3. Receive your personalized prescription formula delivered free to your door
  4. Track your progress with provider check-ins that ensure your formula evolves with your skin

Skincare Tips From The Hello Alpha Team

Here are our top recommendations for success with a prescription formula:

  • Simplify your existing routine when starting prescription skincare—gentle cleanser, your prescription, moisturizer, and sunscreen are often all you need
  • Be consistent with both application and patience
  • Always use sunscreen (minimum SPF 30) daily, as recommended by the Skin Cancer Foundation and American Academy of Dermatology,12 especially as many prescription ingredients increase sun sensitivity
  • Stay hydrated from the inside out—healthy skin starts with overall wellness
  • Communicate with your Hello Alpha provider about any concerns or questions

Remember, prescription skincare isn't just about addressing current concerns—it's preventative care that helps maintain your skin's health for years to come. Your future self will thank you for starting now.

Your skin tells your unique story. 

Start an online skincare visit to make it your best chapter yet.

Please note: The information provided in this blog post is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

Sources:

  1. Kong R, et al. (2016). "A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skin." Journal of Dermatological Science.

  2. Thiboutot D, Gollnick H. (2019). "New insights into the management of acne: An update from the Global Alliance to Improve Outcomes in Acne." Journal of the American Academy of Dermatology.

  3. Baldwin HE, et al. (2018). "40 Years of topical tretinoin use in review." Journal of Drugs in Dermatology.

  4. Mukherjee S, et al. (2006). "Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety." Clinical Interventions in Aging, 1(4):327-348.

  5. Bissett DL, et al. (2005). "Niacinamide: A B vitamin that improves aging facial skin appearance." Dermatologic Surgery, 31:860-866.

  6. Taieb A, et al. (2015). "Superiority of ivermectin 1% cream over metronidazole 0.75% cream in treating inflammatory lesions of rosacea: a randomized, investigator-blinded trial." British Journal of Dermatology, 172(4):1103-1110.

  7. Kircik LH. (2011). "Efficacy and safety of azelaic acid (AzA) gel 15% in the treatment of post-inflammatory hyperpigmentation and acne: a 16-week, baseline-controlled study." Journal of Drugs in Dermatology, 10(6):586-590.

  8. Gao K, et al. (2023). "Oral administration of hyaluronic acid to improve skin conditions via a randomized double-blind clinical test." Skin Research and Technology.

  9. Surjushe A, et al. (2008). "Aloe vera: a short review." Indian Journal of Dermatology, 53(4):163-166.

  10. McDaniel DH, et al. (2017). "Efficacy and tolerability of a double-conjugated retinoid cream vs 1.0% retinol cream or 0.025% tretinoin cream in subjects with mild to severe photoaging." Journal of Cosmetic Dermatology.

  11. Bhawan J, et al. (1995). "Effects of tretinoin on photodamaged skin: A histologic study." Archives of Dermatology, 131(11):1280-1285.

  12. American Academy of Dermatology. (2023). "Sunscreen FAQs." AAD Guidelines of Care. 

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Hello Alpha Team

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